El próximo miércoles 16 de octubre tenemos un nuevo Seminario de Sistemas Complejos en IFIS. Desde las 10:00 AM en la sala 208 del Aulario del Campus Curauma PUCV, Alphonce Opiyo, estudiante del Magíster en Ciencias con mención en Física de nuestro Instituto, presentará “Quantitative analysis of bacterial navegation under hemodynamic conditions”.
Compartimos el abstract de la presentación:
Cancer is a leading cause of death, with nearly 20 million new cases and around 10 million deaths in 2022. Projections
suggest that by 2050, cancer cases will rise to 35 million annually, underscoring the need for better methods of early
detection and treatment. Bacteria, such as engineered Escherichia coli (E. coli), have been explored as potential therapeutic agents for gene delivery and bacteriotherapy. However, their movement within blood-like environments is not fully understood.
This research focuses on analyzing the motility of a genetically engineered E. coli strain using microfluidic chips that mimic the blood’s microcirculatory system, aiming to understand how bacterial movement can be influenced, in a first place, by the presence of red blood cells in a Y-shaped microchannel.